Int Urol Nephrol. 2016 Nov;48(11):1789-1795. Epub 2016 Aug 13.

Canat M¹, Canat L², Öztürk FY³, Eroğlu H^3,4, Atalay HA², Altuntaş Y³.

Author information

• ¹Endocrinology Department, Şişli Etfal Training and Research Hospital, 34371, Şişli/Istanbul, Turkey. mmasumcanat@gmail.com.
• ²Urology Department, Okmeydanı Training and Research Hospital, Şişli, Istanbul, Turkey.
• ³Endocrinology Department, Şişli Etfal Training and Research Hospital, 34371, Şişli/Istanbul, Turkey.
• ⁴Internal Medicine Department, Şişli Etfal Training and Research Hospital, Istanbul, Turkey.

Abstract

PURPOSE:

To assess female sexual functions in women who were affected by vitamin D₃ deficiency.

METHODS:

A total of 50 women with FSD and 58 healthy women controls were included in the study, according to the Female Sexual Function Index (FSFI) questionnaire using a 26.55 cutoff value. Detailed medical histories were obtained from all sexual active women, and all women were evaluated in terms of possible presence of depression with the Beck Depression Inventory (BDI). Serum 25-hydroxyvitamin D₃, follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, total and free testosterone, estradiol, dehydroepiandrosterone-SO₄ (DHEA-SO₄), sex hormone-binding globulin (SHBG), free thyroxine (fT4), and thyroid-stimulating hormone (TSH) levels were measured.

RESULTS:

Mean age of premenopausal women was 34.9 ± 6.3 years. The level of serum 25-hydroxyvitamin D₃ was significantly lower in women with FSD compared with the controls (15.9 ± 8.4 and 26.3 ± 11.7 nmol/L, respectively). Desire (p = 0.0001), arousal (p = 0.0001), lubrication (p = 0.002), orgasm (p = 0.0001), satisfaction (p = 0.018), and pain (p = 0.010) domain scores were also correlated with the levels of serum 25-hydroxyvitamin D₃. The BDI score showed a significant negative correlation with the total FSFI score (r = -0.492, p = 0.0001). The FSFI score not showed a significant correlation with the hormones (p > 0.05).

CONCLUSION:

There is a relationship with FSD and deficiency of vitamin D₃. Also, increased depressive symptoms were associated with FSD.

資料來源：PubMed

連結網址:  https://www.ncbi.nlm.nih.gov/pubmed/27522658